6-Benzoylheteratisine 是天然的Na+ 通道激活剂乌头碱的拮抗剂。
货号:ajcx39882
CAS:99759-48-5
分子式:C29H37NO6
分子量:495.61
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货Background:
6-Benzoylheteratisine is a naturally occurring antagonist of the Na+ channel activator aconitine[1].
6-Benzoylheteratisine (3 μM) decreases the amplitude of the presynaptic fiber spike at all stimulus intensities tested and shiftes the curve to the right[1].6-benzoylheteratisine is capable of inhibiting stimulus-triggered epileptiform activity recorded in CA1 stratum pyramidale[1].
[1]. A Ameri, et al. Interaction of the structurally related aconitum alkaloids, aconitine and 6-benzyolheteratisine, in the rat hippocampus. Eur J Pharmacol. 1999 Dec 15;386(2-3):187-94.