URAT1 inhibitor 1 (1g) 是尿酸转运体 1(URAT1) 的一种抑制剂,其抑制尿酸转运体 1 (URAT1) 的 IC50 值为的 32 nM。URAT1 inhibitor 1 有望用于高尿酸血症痛风的研究。
货号:ajcx39434
CAS:2268720-62-1
分子式:C19H15Br2N5O2S2
分子量:569.29
溶解度:DMSO : 125 mg/mL (219.57 mM; ultrasonic and warming and heat to 60°C)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
URAT1 inhibitor 1 (1g) is a uric acid transporter 1 (URAT1) inhibitor, with an IC50 of 32 nM. URAT1 inhibitor 1 has potential to treat hyperuricemia associated with gout[1].
[1]. Wu JW, et al. Synthesis, biological evaluation and 3D-QSAR studies of 1,2,4-triazole-5-substituted carboxylic acid bioisosteres as uric acid transporter 1 (URAT1) inhibitors for the treatment of hyperuricemia associated with gout. Bioorg Med Chem Lett. 2019 Feb 1;29(3):383-388.