TEAD-IN-2 是一种新型的活性 TEAD 抑制剂,具有口服活性,通过泛素化和/或化合物降解调节转录增强子关联结构域 (TEAD)。TEAD-IN-2 可用于与 TEAD 相关的各种疾病、紊乱或条件的研究。
货号:ajcx39084
CAS:2563849-97-6
分子式:C16H18BrF3N2O
分子量:391.23
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货Background:
TEAD-IN-2 is a novel, orally active inhibitor of transcriptional enhancer associate domain (TEAD) and modulates TEAD by ubiquitination and/or degradation by compounds. TEAD-IN-2 can be used for the research of a variety of diseases, disorders or conditions associated with TEAD[1].
[1]. Alfredo C. Castro, et al. Preparation of heterocyclic compounds as TEAD degraders and uses thereof. Patent wo2022120355A1.