Lorpucitinib 是一种肠道 JAK 激酶的抑制剂,用于炎症性肠病的研究。
货号:ajcx37488
CAS:2230282-02-5
分子式:C22H28N6O2
分子量:408.5
溶解度:DMSO : 250 mg/mL (612.00 mM; Need ultrasonic)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Lorpucitinib is a Gut-Restricted JAK Inhibitor for the research of Inflammatory Bowel Disease[1].
[1]. Leonard KA, Madge LA, Krawczuk PJ, Wang A, Kreutter KD, Bacani GM, Chai W, Smith RC, Tichenor MS, Harris MC, Malaviya R, Seierstad M, Johnson ME, Venable JD, Kim S, Hirst GC, Mathur AS, Rao TS, Edwards JP, Rizzolio MC, Koudriakova T. Discovery of a Gut-Restricted JAK Inhibitor for the Treatment of Inflammatory Bowel Disease. J Med Chem. 2020 Mar 26;63(6):2915-2929.