DB2115 (tertahydrochloride) 是骨髓主调节因子 PU.1 的有效抑制剂。DB2115 (tertahydrochloride) 具有治疗癌症的潜力,包括白血病等血液系统癌症,以及与PU. 1 功能障碍相关的其他疾病 (信息来自专利 WO2017223260A1,compound DB2115)。
货号:ajcx35538
CAS:1366126-19-3
分子式:C32H34Cl4N8O2
分子量:704.48
溶解度:DMSO : 10 mg/mL (14.19 mM; ultrasonic and warming and adjust pH to 2 with HCl and heat to 80°C)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
DB2115 (tertahydrochloride) is a potent inhibitor of myeloid master regulator PU.1. DB2115 (tertahydrochloride) has the potential for the treatment of cancers, including hematologic cancers such as leukemia, as well as other conditions associated with PU. 1 dysfunction (extracted from patent WO2017223260A1, compound DB2115) [1].
[1]. W. David Wilson, et al. Pu.1 inhibitors. Patent WO2017223260A1.