ONO-9780307

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ONO-9780307

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

规格:	98%
分子量:	521.6

包装与价格：

包装	价格(元)
5mg	询价
10mg	询价

ONO-9780307 是一种特异性的 LPA1 (lysophosphatidic acid receptor 1) 拮抗剂，其IC50 的值为 2.7 nM。
货号:ajcx35070
CAS:856691-44-6
分子式:C30H35NO7
分子量：521.6
溶解度:DMSO : 190 mg/mL (364.26 mM; Need ultrasonic)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

ONO-9780307 is a specific synthetic LPA1 (lysophosphatidic acid receptor 1) antagonist with an IC50 value of 2.7 nM[1].

VT107 (0.1~10000 μM; LPA1-B103 and Vector-B103 cells) results in inhibition of Ca2+ mobilization[1].ONO-9780307 is used to solve the LPA1 crystal structure, binds to an orthosteric site in LPA1[1].

[1]. Mizuno H, et al. Lysophospholipid G protein-coupled receptor binding parameters as determined by backscattering interferometry. J Lipid Res. 2019;60(1):212-217.