(R)-(-)-O-Desmethyl Venlafaxine D6 是 (R)-(-)-O-Desmethyl Venlafaxine 的氘代物。O-Desmethyl Venlafaxine 是 Venlafaxine 的活性代谢产物。Venlafaxine 是 5-羟色胺-去甲肾上腺素再摄取抑制剂 (SNRI) 类的抗抑郁剂。
货号:ajcx34316
CAS:1062609-96-4
分子式:C16H19D6NO2
分子量：269.41
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

(R)-(-)-O-Desmethyl Venlafaxine D6 is the deuterium labeled (R)-(-)-O-Desmethyl Venlafaxine. O-Desmethyl Venlafaxine is an active metabolite of Venlafaxine[1]. Venlafaxine is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class[2].

[1]. Yijin Liu, et al. Development of an enantioselective assay for simultaneous separation of venlafaxine and O-desmethylvenlafaxine by micellar electrokinetic chromatography-tandem mass spectrometry: Application to the analysis of drug-drug interaction. J Chromatogr A. 2015 Nov 13;1420:119-28. [2]. F P Bymaste, et al. Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors. Neuropsychopharmacology. 2001 Dec;25(6):871-80.