(R)-BRD3731是一种GSK3的抑制剂,对GSK3β和GSK3α的IC50值分别为1.05和6.7μM。详细信息请参考专利文献US20160375006A1中的化合物273。
货号:ajcx29818
CAS:2056262-08-7
分子式:C24H31N3O
分子量:377.52
溶解度:DMSO: 200 mg/mL (529.77 mM)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
(R)-BRD3731 is a GSK3 inhibitor extracted from patent US20160375006A1, compound example 273, has IC50s of 1.05 and 6.7 μM for GSK3β and GSK3α, respectively[1].
[1]. Scolnick E, et, al. Uses of paralog-selective inhibitors of gsk3 kinases. US20160375006A1.