GS-704277是Remdesivir的丙氨酸代谢产物。Remdesivir是一种具有抗病毒活性的核苷类似物，在体外对SARS-CoV-2(COVID-19)感染具有很高的抑制作用。
货号:ajcx29374
CAS:1911579-04-8
分子式:C15H19N6O8P
分子量：442.32
溶解度:DMSO: soluble
纯度：98%
存储：Store at -20°C
库存：现货

Background:

GS-704277 is an alanine metabolite of Remdesivir. Remdesivir, a nucleoside analogue with effective antiviral activity, is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro[1][2].

[1]. Eastman RT, et al. Remdesivir: A Review of Its Discovery and Development Leading to Emergency Use Authorization for Treatment of COVID-19 [published correction appears in ACS Cent Sci. 2020 Jun 24;6(6):1009]. ACS Cent Sci. 2020;6(5):672-683. [2]. Wang M, et al. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro. Cell Res. 2020 Mar;30(3):269-271.