The phosphatidylinositols (PtdIns) phosphates represent a small percentage of total membrane phospholipids.
货号:ajcx18912
CAS:N/A
分子式:C41H78O19P3•3Na
分子量：1036.9
溶解度:50 mM HEPES*: 8 mg/ml,CHCl3:CH3OH:H2O (3:2:1): 10 mg/ml,PBS (pH 7.2): 1 mg/ml (opaque solution)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

The phosphatidylinositols (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns is phosphorylated to mono- (PtdIns-P; PIP), di- (PtdIns-P2; PIP2) and triphosphates (PtdIns-P3; PIP3). Hydrolysis of PIP2 by PI-specific phospholipase C generates IP3 and diacylglycerol (DAG). The DAG and IP3 produced by this reaction are part of a complex biochemical and signal transduction cascade that is at the frontier of scientific research today.