Clavulanate lithium 是一种高效的 β-lactamase 抑制剂，可作为抗生素。
货号:ajcx15586
CAS:61177-44-4
分子式:C8H8LiNO5
分子量：205.09
溶解度:H2O: 50 mg/mL (243.80 mM); DMSO: 5 mg/mL (24.38 mM; ultrasonic and warming and heat to 80°C)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Clavulanate lithium is a potent β-lactamase inhibitor and acts as an antibiotic[1][2].

Clavulanate lithium has weak antibacterial activity against most organisms when administered alone, but given in combination with beta-lactam antibiotics prevents antibiotic inactivation by microbial lactamase[1].Clavulanate lithium (0.25, 0.5 mg/L) causes a relatively slow inhibition of growth, and a higher concentration (1 mg/L) is only marginally more effective than 0.5 mg/L [2]. Cell Viability Assay[2] Cell Line: L. pneumophila NCTC 1119

[1]. Reading C, et al. Clavulanic Acid: a Beta-Lactamase-Inhibiting Beta-Lactam from Streptomyces clavuligerus. Antimicrob Agents Chemother. 1977 May; 11(5): 852-857. [2]. Stokes DH, et al. Bactericidal effects of amoxycillin/clavulanic acid against intracellular Legionella pneumophila in tissue culture studies. J Antimicrob Chemother. 1989 Apr;23(4):547-56.