Description: Quinapril Hydrate (also known as CI-906, PD-109452-2) is a potent angiotensin-converting enzyme inhibitor with a Ki of 20 μM. Quinapril is a prodrug that has to to be converted to its active metabolite, quinaprilat. Quinapril's target, ACE, catalyses the formation of angiotensin II from its precursor, angiotensin I. Angiotensin II is a potent vasoconstrictor and thus preventing its formation causes vasodilation and an increased capillary blood volume.

References: Cardiovasc Drugs Ther. 2002 Jan;16(1):29-36; Drugs. 2002;62(2):339-85.

Related CAS #: 85441-61-8 (free base) 82586-55-8 (HCl)

纯度：≥98%