Fosravuconazole是ravuconazole的前体物质，具有抗真菌活性。
货号:ajcx13114
CAS:351227-64-0
分子式:C23H20F2N5O5PS
分子量：547.47
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Fosravuconazole is a prodrug of ravuconazole, with antifungal activity.

Fosravuconazole (BMS-379224) is a prodrug of ravuconazole, with antifungal activity[1].

Fosravuconazole (BMS-379224) is rapidly conversed to ravuconazole upon iv administration to rats. Fosravuconazole shows comparable efficacy at inhibiting C. albicans infection model in mice as orally administered ravuconazole[1].

[1]. Ueda Y, et al. Phosphonooxymethyl prodrugs of the broad spectrum antifungal azole, ravuconazole: synthesis and biological properties. Bioorg Med Chem Lett. 2003 Nov 3;13(21):3669-72.