Taniborbactam是一种有效的β-lactamase抑制剂,对β-lactamase不同亚型SHV-5,KPC-2,VIM-2和AmpC的IC50值<100nM,对OXA-1的IC50值为0.1-1μM,可用于细菌感染的研究。
货号:ajcx12790
CAS:1613267-49-4
分子式:C19H28BN3O5
分子量:389.25
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Taniborbactam is a potent inhibitor of β-lactamase, with IC50s of<100 nM for SHV-5, KPC-2, VIM-2, and AmpC β-lactamase, and 0.1 to 1 μM for OXA-1 β-lactamase, used in the research of bacterial infections[1].
Taniborbactam (Example 15) is a potent inhibitor of β-lactamase, with IC50s of<100 nM for SHV-5, KPC-2, VIM-2, and AmpC β-lactamase, and 0.1 to 1 μM for OXA-1 β-lactamase, used in the research of bacterial infections[1].
[1]. Christopher J. Burns, et al. Beta-lactamase inhibitors. WO2014089365A1