GI181771是研究用于治疗肥胖症的胆囊收缩素1(cholecystokinin1)受体激动剂。
货号:ajcx12616
CAS:305366-98-7
分子式:C34H31N5O6
分子量：605.64
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

GI 181771 is a cholecystokinin 1 receptor agonist investigated for the treatment of obesity.

[1]. Myer JR, et al. Species- and dose-specific pancreatic responses and progression in single- and repeat-dose studies with GI181771X: a novel cholecystokinin 1 receptor agonist in mice, rats, and monkeys. Toxicol Pathol. 2014 Jan;42(1):260-74. [2]. Roses AD, et al. Stimulation of cholecystokinin-A receptors with Gl181771X: a failed clinical trial that did not test the pharmacogenetic hypothesis for reduction of food intake. Clin Pharmacol Ther. 2009 Apr;85(4):362-5.