Used in oligonucleotide synthesis
货号:ajcx11378
CAS:
分子式:C37H52N3O5PS
分子量:681.86
溶解度:soluble in acetonitrile, dichloromethane
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Aminolink phosphoramidite for oligonucleotide synthesis. DMS(O)MT is a special protective group similar to traditional MMT, but designed as an improved alternative to it. DMS(O)MT aminolink is fully compatible with standard coupling, deblock, and purification protocols. However, DMS(O)MT group is much better suited for DMT-on and cartridge purification of amino-oligonucleotides because of higher stability, and better oligonucleotide recovery. Oligonucleotides containing DMS(O)MT are more stable in solution than MMT analogs.
In case of cartridge purification, DMS(O)MT protection allows for 2-3 fold increase of oligonucleotide yield, making this reagent a unique solution for high-throughput manufacturing of amino-oligonucleotides.