pyCTZ (Pyridyl CTZ) TFA，一种腔肠素 (CTZ) 类似物，是 ATP 非依赖性的 LumiLuc 荧光素酶的吡啶基底物。pyCTZ TFA 在荧光素酶的存在下会产生强烈的蓝色生物发光。pyCTZ TFA 可用于基于水母发光蛋白的钙感测。
货号:ajcx35132
CAS:N/A
分子式:C27H21F3N4O3
分子量：506.48
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

pyCTZ (Pyridyl CTZ) TFA, a pyridyl Coelenterazine (CTZ) analog, and is an ATP-independent pyridyl substrate of LumiLuc luciferase. pyCTZ TFA generates strong blue bioluminescence in the presence of luciferases. pyCTZ TFA can be used for aequorin-based calcium sensing[1].

pyCTZ TFA is comparable to native CTZ for bioluminescence intensity when pairs with aequorin[1].

[1]. Yeh HW, et, al. ATP-Independent Bioluminescent Reporter Variants To Improve in Vivo Imaging. ACS Chem Biol. 2019 May 17;14(5):959-965.