R1498 is an inhibitor of cyclin-dependent kinase 2 (CDK2). It is well-tolerated and orally bioavailable for hepatocellular carcinoma and gastric cancer treatment and acts via targeting angiogenesis and mitosis pathways. References: Thunhorst RL, Beltz TG, Johnson AK. Effects of aging on mineralocorticoid-induced salt appetite in rats. Am J Physiol Regul Integr Comp Physiol. 2013 Dec 15;305(12):R1498-505. doi: 10.1152/ajpregu.00349.2013. Epub 2013 Oct 16. PubMed PMID: 24133100; PubMed Central PMCID: PMC3882696.
纯度:≥98%
CAS:303196-31-8