β-catenin-IN-2 是一种有效的 β-catenin 抑制剂,化合物 H1B1,源于专利 US20150374662A1。β-catenin-IN-2 可用于结直肠癌的研究。
货号:ajcx33710
CAS:1458664-10-2
分子式:C15H14FN3
分子量:255.29
溶解度:DMSO : 83.33 mg/mL (326.41 mM; Need ultrasonic)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
β-catenin-IN-2 is a potent β-catenin inhibitor, compound H1B1, extracted from patent US20150374662A1. β-catenin-IN-2 can be used for the study of colorectal cancer[1].
β-catenin-IN-2 (10-40 μM) suppresses the transcriptional activity of the β-catenin/Tcf-4 in a dose-dependent manner in HCT116 cells[1].
[1]. Ann Marie Bode, et al. Inhibitors of beta-catenin in treatment of colorectal cancer. Patent US20150374662A1.