Fmoc-NH-PEG6-CH2CH2COOH是一种可降解的ADClinker,用于抗体药物偶联物(ADC)合成。
货号:ajcx31814
CAS:882847-34-9
分子式:C30H41NO10
分子量:575.65
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Fmoc-NH-PEG6-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
[1]. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.