Cytidine5'-diphosphatetrisodiumsalt(CDP)是由尿苷单磷酸激酶(UMPK)催化的磷酸基团从ATP转移到胞苷单磷酸(CMP)产生的。Cytidine5'-diphosphatetrisodiumsalt可用于生产胞苷三磷酸(CTP)以合成DNA和RNA。
货号:ajcx31798
CAS:34393-59-4
分子式:C9H12N3Na3O11P2
分子量：469.12
溶解度:H2O: 250 mg/mL (532.91 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Cytidine 5'-diphosphate trisodium salt (CDP) is produced by the transfer of phosphoryl group from ATP to cytidine monophosphate (CMP) catalyzed by uridine monophosphate kinase (UMPK). Cytidine 5′-diphosphate can be used to produce Cytidine triphosphate (CTP) for synthesis of DNA and RNA[1][2].

CDP-ribitol can be used for the Diagnostics and research of CDP-l-ribitol pyrophosphorylase A (CRPPA) muscular dystrophy[3].

[1]. Moffatt BA, et, al. Purine and pyrimidine nucleotide synthesis and metabolism. Arabidopsis Book. 2002;1:e0018. [2]. Salvador-Silva M, et, al. Microglial cells in the retina of Carassius auratus: effects of optic nerve crush. J Comp Neurol. 2000 Feb 21;417(4):431-47. [3]. Tol W, et, al. Cytidine Diphosphate-Ribitol Analysis for Diagnostics and Treatment Monitoring of Cytidine Diphosphate-l-Ribitol Pyrophosphorylase A Muscular Dystrophy. Clin Chem. 2019 Oct;65(10):1295-1306.