N-DesmethylGalanthamine是的Galanthamine的代谢物。Galanthamine是一种有效的乙酰胆碱酯酶(AChE)抑制剂,IC50为500nM。
货号:ajcx31164
CAS:41303-74-6
分子式:C16H19NO3
分子量:273.33
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货Background:
N-Desmethyl Galanthamine is a metabolite of Galanthamine. Galanthamine is a potent acetylcholinesterase (AChE) inhibitor with an IC50 of 500 nM[1][2].
[1]. Bachus R, et al. The O-demethylation of the antidementia drug galanthamine is catalysed by cytochrome P450 2D6. Pharmacogenetics. 1999;9(6):661-668.
[2]. Melanie-Jayne R. Howes, et al. Acetylcholinesterase inhibitors of natural origin. International Journal of Research in Pharmaceutical and Biomedical Sciences 3(SI 1):67-86.