Ferrousbisglycinate是一种具有口服活性的铁强化剂和补充剂。Ferrousbisglycinate可用于缺铁性贫血的研究。
货号:ajcx30646
CAS:20150-34-9
分子式:C4H6FeN2O4
分子量：201.95
溶解度:H2O: 35.71 mg/mL (176.83 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Ferrous bisglycinate is an orally active iron fortificants and therapeutic iron supplements. Ferrous bisglycinate can be used for the research of iron deficiency anemia[1][2].

Ferrous bisglycinate (25-200 μM; 2 h) does not affect the Caco-2 cells viability[2].Ferrous bisglycinate (25 μM; 2 h) increases ferritin content in the Caco-2 cells[2]. Cell Viability Assay[2] Cell Line: Caco-2 cells

Ferrous bisglycinate (500 mg/kg iron; p.o.) exerts a protective effect on colitis in mice[3]. Animal Model: Female C57BL/6 mice are induced colitis by dextran sodium sulfate (DSS)[3]

参考文献:
[1]. Ferrari P, et, al. Treatment of mild non-chemotherapy-induced iron deficiency anemia in cancer patients: comparison between oral ferrous bisglycinate chelate and ferrous sulfate. Biomed Pharmacother. 2012 Sep; 66(6): 414-8.
[2]. Yu X, et, al. Iron Transport from Ferrous Bisglycinate and Ferrous Sulfate in DMT1-Knockout Human Intestinal Caco-2 Cells. Nutrients. 2019 Feb 26; 11(3): 485.
[3]. Constante M, et, al. Iron Supplements Modulate Colon Microbiota Composition and Potentiate the Protective Effects of Probiotics in Dextran Sodium Sulfate-induced Colitis. Inflamm Bowel Dis. 2017 May; 23(5): 753-766.