An active metabolite of sibutramine
货号:ajcx26658
CAS:84467-94-7
分子式:C16H24ClN • HCl
分子量：302.3
溶解度:Water: soluble
纯度：98%
存储：Store at -20°C
库存：
现货Background:
Desmethyl sibutramine is an active metabolite of sibutramine.1It prevents reserpine-induced ptosis in rats (ED50= 4.2 mg/kg) and decreases immobility in the Porsolt learned helplessness test in mice when administered at a dose of 10 mg/kg.
1.Luscombe, G.P., Hopcroft, R.H., Tomas, P.C., et al.The contribution of metabolites to the rapid and potent down-regulation of rat cortical β-adrenoceptors by the putative antidepressant sibutramine hydrochlorideNeuropharmacology28(2)129-134(1989)
