16-Epiestriol 是内源性雌激素雌酮的代谢产物，具有抗菌和抗炎作用。
货号:ajcx25114
CAS:547-81-9
分子式:C18H24O3
分子量：288.4
溶解度:Ethanol: 1 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

16-Epiestriol is a metabolite of the endogenous estrogen estrone .¹It is formed from estroneviaa 16β-hydroxy estrone intermediate by reduction of the C-17 ketone. 16-Epiestriol (200 µg/ml) inhibits the growth of carbapenem-resistantA. baumannii.²It inhibits carrageenan-induced paw edema in rats when administered at a dose of 20 mg/kg.³Unlike hydrocortisone, 16-epiestriol (240 µg/animal) does not increase plasma or liver glucose levels in adrenalectomized rats.

1.Brinton, L.A., Trabert, B., Anderson, G.L., et al.Serum estrogens and estrogen metabolites and endometrial cancer risk among postmenopausal womenCancer Epidemiol. Biomarkers Prev.25(7)1081-1089(2016) 2.Skariyachan, S., Muddebihalkar, A.G., Badrinath, V., et al.Natural epiestriol-16 act as potential lead molecule against prospective molecular targets of multidrug resistant Acinetobacter baumannii-Insight from in silico modelling and in vitro investigationsInfect. Genet. Evol.82104314(2020) 3.Latman, N.S., Kishore, V., and Bruot, B.C.16-Epiestriol: An anti-inflammatory steroid without glycogenic activityJ. Pharm. Sci.83(6)874-877(1994)