糠酸莫米松-d3 (Sch32088-d3) 是一种氘标记的糠酸莫米松。
货号:ajcx24064
CAS:N/A
分子式:C27H27Cl2D3O6
分子量：524.5
溶解度:Acetonitrile:Methanol (1:1): soluble
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Mometasone furoate-d₃is intended for use as an internal standard for the quantification of mometasone furoate by GC- or LC-MS. Mometasone furoate is a prodrug form of the synthetic glucocorticoid mometasone .¹Intranasal administration of mometasone furoate (1 µg/nostril) reduces the frequency of sneezing and nasal rubbing in a rat model of histamine-induced allergic rhinitis.²Topical application of mometasone furoate reduces croton oil-induced ear edema in mice (ED₅₀= 0.31 µg/ml).³Formulations containing mometasone furoate have been used in the treatment of allergic rhinitis, atopic dermatitis, and asthma.

1.Smith, C.L., and Kreutner, W.In vitro glucocorticoid receptor binding and transcriptional activation by topically active glucocorticoidsArzneimittel-Forschung48(9)956-960(1998) 2.Altunta?, E.E., Do?an, O.T., SaraÇ, B., et al.The effects of mometasone furoate and strontium chloride in a rat model of allergic rhinitisEar Nose Throat J.97(1-2)E1-E7(2018) 3.Ogawa, M.Dissociation of local anti-inflammatory effect and systemic effects of mometasone furoate in miceImmunopharmacol. Immunotoxicol.31(4)601-606(2009)