3β-OH-7-Oxocholenic Acid

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规格:	98%
分子量:	388.5

包装与价格：

包装	价格(元)
500ug	询价
1mg	询价
5mg	询价

A bile acid
货号:ajcx20492
CAS:25218-38-6
分子式:C24H36O4
分子量：388.5
溶解度:Acetonitrile: 1mg/mL,Ethanol: 1mg/mL,Methanol: 1mg/mL
纯度：98%
存储：Store at -20°C
库存：现货

Background:

3β-OH-7-Oxocholenic acid is a bile acid.1 It is also a metabolite of 7β-hydroxy cholesterol in rats. Conjugated forms of 3β-OH-7-oxocholenic acid have been found in the urine of patients with Neimann-Pick disease type C.2,3

|1. Norii, T., Yamaga, N., and Yamasaki, K. Metabolism of 7β-hydroxycholesterol-4-14C in rat. Steroids 15(3), 303-326 (1970).|2. Alvelius, G., Hjalmarson, O., Griffiths, W.J., et al. Identification of unusual 7-oxygenated bile acid sulfates in a patient with Niemann-Pick disease, type C. J. Lipid Res. 42(10), 1571-1577 (2001).|3. Maekawa, M., Omura, K., Sekiguchi, S., et al. Identification of two sulfated cholesterol metabolites found in the urine of a patient with Niemann-Pick disease type C as novel candidate diagnostic markers. Mass Spectrom. (Tokyo) 5(2), S0053 (2016).