Ac-ANW-AMC 是免疫蛋白酶体的荧光底物。
货号:ajcx18028
CAS:N/A
分子式:C30H32N6O7
分子量：588.6
溶解度:10mM in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Ac-ANW-AMC is a fluorogenic substrate for the β5i/LMP7 subunit of the 20S immunoproteasome. [1] Upon cleavage, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify the activity of the β5i/LMP7 subunit of the 20S immunoproteasome. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.

参考文献
[1]. Winter, M.B., La Greca, F., Arastu-Kapur, S., et al. Immunoproteasome functions explained by divergence in cleavage specificity and regulation. eLife 6:e27364, (2017).