Di-, tri-, and tetramethoxystilbenes potently inhibit cytochrome P450 1B1 (CYP1B1), an isoform involved in estrogen metabolism and implicated in hormone-mediated cancers.
货号:ajcx17604
CAS:N/A
分子式:C17H18O4
分子量：286.3
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Di-, tri-, and tetramethoxystilbenes potently inhibit cytochrome P450 1B1 (CYP1B1), an isoform involved in estrogen metabolism and implicated in hormone-mediated cancers. CAY10668 is a 4-hydroxylated form of 2,2',6'-trimethoxy-trans-stilbene. The 4-methoxylated form of the same trans-stilbenoid inhibits CYP1B1 (IC50 = 1.77 nM), suggesting that this compound may also be an inhibitor of CYP1B1.