Decoglurant (RO4995819) 是 mGluR2 和 mGluR3 的一种负变构调制器。Decoglurant 是一种抗抑郁药。
货号:ajcx16874
CAS:911115-16-7
分子式:C21H11F6N5
分子量:447.34
溶解度:DMSO: 250 mg/mL (558.86 mM)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Decoglurant (RO4995819) is a negative allosteric modulator of mGluR2 and mGluR3. Decoglurant is developed as an antidepressant[1].
[1]. Wilkinson ST, et al. A new generation of antidepressants: an update on the pharmaceutical pipeline for novel and rapid-acting therapeutics in mood disorders based on glutamate/GABA neurotransmitter systems. Drug Discov Today. 2019 Feb;24(2):606-615.