(rel)-AR234960 是AR234960 的相对活性构型。AR234960 是一种非肽类的MAS (一种G蛋白的偶联受体) 的激动剂，在HEK293-MAS 细胞和成人心肌成纤维细胞中，通过 ERK1/2 信号通路中上调 CTGF mRNA 和蛋白水平。
货号:ajcx16870
CAS:1408311-94-3
分子式:C27H30FN5O5S
分子量：555.62
溶解度:DMSO: 25 mg/mL (44.99 mM; ultrasonic and heat to 80°C)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

(rel)-AR234960 is an active relative configuration of AR234960. AR234960, a non-peptide MAS (a G protein-coupled receptor) agonist, increases both mRNA and protein levels of CTGF via ERK1/2 signaling in HEK293-MAS cells and adult human cardiac fibroblasts[1].

[1]. Chatterjee A, et al. Connective tissue growth factor dependent collagen gene expression induced by MAS agonist AR234960 in human cardiac fibroblasts. PLoS One. 2017 Dec 29;12(12):e0190217.