Vapendavir diphosphate (BTA798 diphosphate) 是一种有效的肠病毒衣壳粘合剂 (CB)。Vapendavir diphosphate (BTA798 diphosphate) 可抑制 EV71 的复制，对 EV71 不同毒株的 EC50 值为0.5-1.4 μM。
货号:ajcx16268
CAS:1198151-75-5
分子式:C21H32N4O11P2
分子量：578.45
溶解度:DMSO: 6.75 mg/mL (11.67 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Vapendavir diphosphate (BTA798 diphosphate) is a potent enteroviral capsid binder (CB). Vapendavir diphosphate (BTA798 diphosphate) possesses potent antiviral activity for enterovirus 71 (EV71) replication, with EC50 values of 0.5-1.4 μM in different EV71 strains[1][2].

[1]. Tijsma A, et al. The capsid binder Vapendavir and the novel protease inhibitor SG85 inhibit enterovirus 71 replication. Antimicrob Agents Chemother. 2014 Nov;58(11):6990-2. [2]. Sun L, et al. Antiviral Activity of Broad-Spectrum and Enterovirus-Specific Inhibitors against Clinical Isolates of Enterovirus D68. Antimicrob Agents Chemother. 2015 Dec;59(12):7782-5.