Ibrutinib-MPEA 是 Ibrutinib的衍生物。Ibrutinib 是Bruton 酪氨酸激酶 (BTK) 的一种共价和不可逆抑制剂,可用于治疗血液恶性肿瘤。
货号:ajcx14324
CAS:1710768-30-1
分子式:C32H39N9O2
分子量:581.71
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Ibrutinib-MPEA (Compound 20) is ibrutinib derivative. Ibrutinib is a covalent and irreversible inhibitor of Bruton's tyrosine kinase (BTK) that has been used to treat haematological malignancies[1].
[1]. Liu N, et al. Direct and two-step bioorthogonal probes for Bruton's tyrosine kinase based on ibrutinib: a comparative study. Org Biomol Chem. 2015 May 14;13(18):5147-57.