PGAM1-IN-1 是一种有效的磷酸甘油酸变位酶 1 (PGAM1) 抑制剂,IC50 为 6.4 μM。
货号:ajcx14078
CAS:2438637-65-9
分子式:C19H11ClFNO6S
分子量:435.81
溶解度:DMSO: 5 mg/mL (11.47 mM and warming)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
PGAM1-IN-1 is a phosphoglycerate mutase 1 (PGAM1) inhibitor with an IC50 of 6.4 μM[1].
IC50: 6.4 μM (PGAM1)[1]
PGAM1-IN-1 (Compound 9h) inhibits H1299 proliferation with an IC50 of 14.1±1.9 μM[1].
[1]. Wang P, et al. The Design and Synthesis of N-Xanthone Benzenesulfonamides as Novel Phosphoglycerate Mutase 1 (PGAM1) Inhibitors. Molecules. 2018 Jun 8;23(6). pii: E1396.