G150 是一种有效、高选择性的 h-cGAS 抑制剂，IC50 值为 10.2 nM，用于抑制 dsDNA 引发的干扰素表达。
货号:ajcx13910
CAS:2369751-30-2
分子式:C18H16Cl2N4O2
分子量：391.25
溶解度:DMSO: 125 mg/mL (319.49 mM)
纯度：98%
存储：Store at -20°C
库存：
现货Background:
G150 is a potent and highly selective human cyclic GMP-AMP synthase (h-cGAS) inhibitor for repression of dsDNA-triggered interferon expression, with an IC50 of 10.2 nM[1].
IC50: 10.2 nM (h-cGAS)[1]
[1]. Lama L, et al. Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression. Nat Commun. 2019 May 21;10(1):2261.
