Bacterial Sortase Substrate III, Abz/DNP 是一种内部淬灭的荧光肽底物。金黄色葡萄球菌转肽酶分选酶A (SrtA) 与 Bacterial Sortase Substrate III, Abz/DNP 反应，裂解并催化苏氨酸的羧基与细胞壁交联桥的氨基之间形成酰胺键。可以在 Ex/Em=320 nm/420 nm 下检测该底物的切割。
货号:ajcx13746
CAS:N/A
分子式:C41H57N11O14
分子量：928
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Bacterial Sortase Substrate III, Abz/DNP is an internally quenched fluorescent peptide substrate. Staphylococcus aureus transpeptidase sortase A (SrtA) reacts with its native substrate Bacterial Sortase Substrate III, Abz/DNP, cleaving it and catalyzing the formation of an amide bond between the carboxyl group of threonine and the amino group of cell-wall crossbridges. Cleavage of this substrate can be monitored at Ex/Em=320 nm/420 nm.

[1]. Zhang J, et al. Antiinfective therapy with a small molecule inhibitor of Staphylococcus aureus sortase. Proc Natl Acad Sci U S A. 2014 Sep 16;111(37):13517-22.