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FABPs ligand 6
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
FABPs ligand 6图片
规格:98%
分子量:458.52
包装与价格:
包装价格(元)
5mg询价
10mg询价
25mg询价

FABPs ligand 6 (MF6) 是一种 FABP5 和 FABP7 抑制剂,KD 值分别为 874 nM 和 20 nM。FABPs ligand 6 可用于多发性硬化症的研究。
货号:ajcx39354
CAS:N/A
分子式:C28H27FN2O3
分子量:458.52
溶解度:DMSO : 250 mg/mL (545.23 mM; Need ultrasonic)
纯度:98%
存储:Store at -20°C
库存:现货

Background:

FABPs ligand 6 (MF6) is an FABP5 and FABP7 inhibitor with KD values of 874 nM and 20 nM, respectively. FABPs ligand 6 can be used for multiple sclerosis research[1].

FABPs ligand 6 (MF6) rescues mitochondrial function by blocking voltagedependent anion channel (VDAC)-1-dependent mitochondrial macropore formation induced by psychosine in KG-1C cells, a FABP5- mediated injury[1].

MF 6 (1 mg/kg; i.g.; daily for 4 weeks) improves the severity of EAE (experimental autoimmune encephalomyelitis) and attenuates oxidative levels and the inflammatory response[1].

[1]. Cheng A, et al. A novel fatty acid-binding protein 5 and 7 inhibitor ameliorates oligodendrocyte injury in multiple sclerosis mouse models. EBioMedicine. 2021 Oct;72:103582.

 
 
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