C12-200 是一种可电离阳离子类脂质和辅助脂质。C12-200 通常用于 mRNA 传递。
货号:ajcx36928
CAS:1220890-25-4
分子式:C70H145N5O5
分子量:1136.93
溶解度:DMSO : 100 mg/mL (87.96 mM; Need ultrasonic)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
C12-200 is a benchmark ionizable cationic lipidoid along with helper lipids. C12-200 is commonly used for mRNA delivery[1][2].
[1]. Khare P, et al. Development of Lipidoid Nanoparticles for siRNA Delivery to Neural Cells. AAPS J. 2021;24(1):8. Published 2021 Dec 6.
[2]. DeRosa F, et al. Therapeutic efficacy in a hemophilia B model using a biosynthetic mRNA liver depot system. Gene Ther. 2016;23(10):699-707.