TAK-778, a derivative of ipriflavone, has been shown to induce bone growth both in vitro and in vivo. Recently, it has been shown that TAK-778 can enhance osteoblast differentiation of human bone marrow cells via an estrogen receptor (ER)-dependent pathway. TAK-778 enhanced bone formation in OVX rats and that this effect was dependent on an ER-mediated pathway.
理化性质和储存条件
| Molecular Weight: 505.52
Formula: C24H28NO7PS
CAS No.: 180185-61-9
SMILES: O=C(NC1=CC=C(CP(OCC)(OCC)=O)C=C1)[C@@H](C2)S[C@@H](C)C(C3=C2C=C4OCOC4=C3)=O |
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| Storage | -20℃ for 3 years in powder form |
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| -80℃ for 2 years in solvent |
| Technical Information | TAK-778 ; TAK 778 ; TAK778 |
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