NF-&kappaβactivator 1

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规格:	98%
分子量:	314.33

包装与价格：

包装	价格(元)
5mg	询价
10mg	询价
25mg	询价
50mg	询价
100mg	询价

NF-κβ activator 1 是一种有效的 NF-κβ 激活剂，EC50 为 0.9 μM，NF-κβ activator 1 诱导超氧化物歧化酶 (SOD)2 mRNA表达。
货号:ajcx33536
CAS:2387524-59-4
分子式:C16H11FN2O2S
分子量：314.33
溶解度:DMSO : 125 mg/mL (397.67 mM; Need ultrasonic)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

NF-κβ activator 1 is a potent NF-κβ activator with an EC50 of 0.9 μM. NF-κβ activator 1 induces superoxide dismutase (SOD)2 mRNA expression[1].

NF-κβ activator 1 (compound 32) (1 μM; 6 hours) induces SOD2 mRNA expression in SH-SY5Y neuroblastoma cells[1].

[1]. Mathew B, et al. Structure-activity relationship (SAR) studies of N-(3-methylpyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine (SRI-22819) as NF-?B activators for the treatment of ALS [published online ahead of print, 2020 Oct 22]. Eur J Med Chem. 2020;112952.