PioglitazoneD4(U72107D4)是一种Pioglitazone氘代物。Pioglitazone(U72107)是一种有效的选择性PPARγ激动剂，高亲和力结合到PPARγ配体结合域，作用于人和鼠PPARγ，EC50分别为0.93和0.99μM。
货号:ajcx31304
CAS:1134163-29-3
分子式:C19H16D4N2O3S
分子量：360.46
溶解度:DMF: 2.5 mg/ml,DMSO: 2.5 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Pioglitazone D4 (U 72107 D4) is a deuterium labeled Pioglitazone. Pioglitazone (U 72107) is a potent and selective PPARγ agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 and 0.99 μM for human and mouse PPARγ, respectively[1].

[1]. Kuwabara K, et al. A novel selective peroxisome proliferator-activated receptor alpha agonist, 2-methyl-c-5-[4-[5-methyl-2-(4-methylphenyl)-4-oxazolyl]butyl]-1,3-dioxane-r-2-carboxylic acid (NS-220), potently decreases plasma triglyceride and glucose leve