A cationic lipidoid
货号:ajcx25442
CAS:2227008-67-3
分子式:C44H83N3O4S2
分子量：782.3
溶解度:Chloroform: 100 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

93-O17S is a chalcogen-containing cationic lipidoid.¹It has been used in the synthesis of lipid nanoparticles (LPNs) for the delivery of Cre recombinase and ribonucleoproteins for genome editing in mice. LPNs containing 93-O17S have been used for the intratumoral delivery of cGAMP to enhance cross-presentation of tumor antigens and stimulation of interferon genes (STING) activation in a B16/F10 murine melanoma model.²

1.Li, Y., Yang, T., Yu, Y., et al.Combinatorial library of chalcogen-containing lipidoids for intracellular delivery of genome-editing proteinsBiomaterials178652-662(2018) 2.Chen, J., Qiu, M., Ye, Z., et al.In situ cancer vaccination using lipidoid nanoparticlesSci. Adv.7(19)eabf1244(2021)