An internal standard for the quantification of roflumilast
货号:ajcx23440
CAS:1398065-69-4
分子式:C17H10Cl2D4F2N2O3
分子量：407.2
溶解度:DMF: 30 mg/ml,DMSO: 20 mg/ml,Ethanol: 10 mg/ml
纯度：98%
存储：Store at -20°C
库存：
现货Background:
Roflumilast-d4is intended for use as an internal standard for the quantification of roflumilast by GC- or LC-MS. Roflumilast is a potent, cell-permeable inhibitor of PDE4 (IC50=<1 nm for both human pde4b and pde4d).1It is selective for PDE4, with IC50values against other PDE forms being greater than 10 μM.
1.Card, G.L., England, B.P., Suzuki, Y., et al.Structural basis for the activity of drugs that inhibit phosphodiesterasesStructure12(12)2233-2247(2004)
