A neuropeptide with diverse biological activities
货号:ajcx21932
CAS:N/A
分子式:C40H77NO2
分子量:604
溶解度:DMF: >20 mg/ml,DMSO: >20 mg/ml,Ethanol: >30mg/ml,Ethanol:PBS (pH 7.2) (1:1): 0.5 mg/ml,PBS (pH 7.2):<50μg/ml
纯度:98%
存储:Store at -20°C
库存:
现货Background:
C22:1 1-Deoxyceramide (m18:1/22:1) is a long-chain atypical ceramide containing a 1-deoxysphingosine (m18:1(4E)) backbone. 1-Deoxysphingolipids are formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis.1,2
1.Steiner, R., Saied, E.M., Othman, A., et al.Elucidating the chemical structure of native 1-deoxysphingosineJ. Lipid Res.57(7)1194-1203(2016)
2.Alecu, I., Othman, A., Penno, A., et al.Cytotoxic 1-deoxysphingolipids are metabolized by a cytochrome P450-dependent pathwayJ. Lipid Res.58(1)60-71(2017)