17,20-dimethyl PGF1α is an analog of the limaprost family with structural modifications intended to give it a prolonged half-life and greater potency.
货号:ajcx17808
CAS:N/A
分子式:C22H40O5
分子量:384.6
溶解度:DMF: >30 mg/ml (from Limaprost),DMSO: >130 mg/ml (from Limaprost),Ethanol: >50 mg/ml (from Limaprost),PBS pH 7.2: >2 mg/ml (from Limaprost)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
17,20-dimethyl PGF1α is an analog of the limaprost family with structural modifications intended to give it a prolonged half-life and greater potency. Limaprost is an analog of PGE1 which is orally active in both rats and guinea pigs. The additional methyl groups in the lower side chain confer a 10-1,000 fold increase in potency over the parent compound. 17,20-dimethyl PGF1α has lower side chain modifications identical to limaprost. There are no published reports describing the pharmacology of 17,20-dimethyl PGF1α.