Anakinra (Raleukin) 是重组的、非溶酶化的 白细胞介素-1受体 (IL-1R) 的拮抗剂。Anakinra 是第一个用于阻断促炎作用的生物制剂。
货号:ajcx16442
CAS:143090-92-0
分子式:C759H1186N208O232S10
分子量:17257.6
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Anakinra (Raleukin) is a recombinant, nonglycosylated human interleukin-1 receptor (IL-1R) antagonist. Anakinra is the first biological agent to block the pro-inflammatory effects[1][2].
参考文献:
[1]. Cvetkovic RS, et al. Anakinra. BioDrugs. 2002;16(4):303-11; discussion 313-4.
[2]. McCall M, et al. Anakinra potentiates the protective effects of etanercept in transplantation of marginal mass human islets in immunodeficient mice. Am J Transplant. 2012 Feb;12(2):322-9.