PEG3-C4-OBn 是一种 PEG 类的 PROTAC 连接桥。PEG3-C4-OBn 可用于合成 PROTAC SGK3 degrader-1 。PROTAC SGK3 degrader-1 是一种 PROTAC，专门降解 SGK3。
货号:ajcx16406
CAS:2381196-79-6
分子式:C17H28O4
分子量：296.4
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

PEG3-C4-OBn is a polyethylene glycol (PEG)-based PROTAC linker. PEG3-C4-OBn can be used in the synthesis of the PROTAC SGK3 degrader-1 . PROTAC SGK3 degrader-1 is a potent SKG3 degrader based on PROTAC[1][2].

[1]. Tovell H, et al. Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTAC Degrader. ACS Chem Biol. 2019 Sep 5. [2]. Tovell H, et al. Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTAC Degrader. ACS Chem Biol. 2019 Sep 20;14(9):2024-2034.