G3-C12(TFA)是galectin-3结合肽，Kd值为88nM，具有抗肿瘤活性。
货号:ajcx13482
CAS:N/A
分子式:C74H115N23O23S2.C2HF3O2
分子量：1873
溶解度:H2O : ≥ 50 mg/mL (26.70 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

G3-C12 (TFA) is a galectin-3 binding peptide, with Kd of 88 nM, and shows anticancer activity.

G3-C12 (TFA) is a galectin-3 binding peptide, with high affinity (Kd) of 88 nM, but shows no affinity for other galectin family members or to other lectins. G3-C12 (TFA) bearing opolymers N-(2-hydroxypropyl)methacrylamide (HPMA) potently and selectively targets colorectal cancer (CRC) tumour cells over-expressing galectin-3 and displays superior targetability to galectin-3 compared to the galactose bearing copolymer[1].

[1]. Kopansky E, et al. Peptide-directed HPMA copolymer-doxorubicin conjugates as targeted therapeutics for colorectal cancer. J Drug Target. 2011 Dec;19(10):933-43.