TSPO配体2是AUTAC1的配体。 AUTAC1 含有一个对氟苄基鸟嘌呤 (FBnG) 和一个烟曲霉醇部分,可沉默 HeLa 细胞中的内源性 MetAP2。
货号:ajcx39032
CAS:1160640-95-8
分子式:C23H29NO8
分子量:447.48
溶解度:DMSO : 50 mg/mL (111.74 mM; ultrasonic and warming and heat to 70°C)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
TSPO ligand-2 is a ligand of AUTAC1. AUTAC1 contains an p-fluorobenzylguanine (FBnG) and a Fumagillol moiety, which can silence endogenous MetAP2 in HeLa cells[1].
[1]. Takahashi D, et al. AUTACs: Cargo-Specific Degraders Using Selective Autophagy. Mol Cell. 2019 Dec 5;76(5):797-810.e10.