Benzyl-PEG4-acid 是一种基于PEG 的 PROTAC linker,可用于 PROTAC 的合成。
货号:ajcx39026
CAS:127457-64-1
分子式:C16H24O6
分子量:312.36
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Benzyl-PEG4-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
[1]. Lepage ML, et al. Design, synthesis and photochemical properties of the first examples of iminosugar clustersbased on fluorescent cores. Beilstein J Org Chem. 2015 May 6;11:659-67.